Application
Western blot analysis of ACOX1 expression in non-transfected (A) and human ACOX1 transfected (B) 293 whole cell lysates.| Product Name | ACOX1 Antibody (A-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of ACOX1 of human origin by WB, IP and ELISA |
| Modification Notes | ACOX1 (acyl-coenzyme A oxidase 1), also known as SCOX or PALMCOX, is a 660 amino acid protein that localizes to the peroxisome and belongs to the acyl-CoA oxidase family. Existing as two alternatively spliced isoforms, ACOX1 uses FAD as a cofactor to catalyze the desaturation of very long chain acyl-CoA proteins to 2-trans-enoyl-CoA proteins, a reaction that utilizes oxygen and produces hydrogen peroxide. Defects in the gene encoding ACOX1 are the cause of pseudoneonatal adrenoleukodystrophy (pseudo-NALD), which is a single-enzyme disorder that is characterized by seizures, mental retardation, leukodystrophy, mild hepatomegaly and hearing deficits. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ACOX1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of ACOX1 of human origin by WB, IP and ELISA |
| Entrez Gene | 51 |
|---|
Application
Western blot analysis of ACOX1 expression in non-transfected (A) and human ACOX1 transfected (B) 293 whole cell lysates.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
