Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining of neuronal and glial cells.| Product Name | ACOX1 Antibody (H-140) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 436-571 mapping near the C-terminus of ACOX1 of human origin |
| Modification Notes | ACOX1 (acyl-coenzyme A oxidase 1), also known as SCOX or PALMCOX, is a 660 amino acid protein that localizes to the peroxisome and belongs to the acyl-CoA oxidase family. Existing as two alternatively spliced isoforms, ACOX1 uses FAD as a cofactor to catalyze the desaturation of very long chain acyl-CoA proteins to 2-trans-enoyl-CoA proteins, a reaction that utilizes oxygen and produces hydrogen peroxide. Defects in the gene encoding ACOX1 are the cause of pseudoneonatal adrenoleukodystrophy (pseudo-NALD), which is a single-enzyme disorder that is characterized by seizures, mental retardation, leukodystrophy, mild hepatomegaly and hearing deficits. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of ACOX1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 436-571 mapping near the C-terminus of ACOX1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 436-571 mapping near the C-terminus of ACOX1 of human origin |
| Entrez Gene | 51 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining of neuronal and glial cells.| Application Notes | recommended for detection of ACOX1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
