| Product Name | BMCP1 (UCP5) Antibody (O-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of BMCP1 (UCP5) of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine |
| Modification Notes | Brain mitochondrial carrier protein 1 (BMCP1), also designated uncoupling protein 5 (UCP5) or solute carrier family 25 member 14 (SLC25A14), is a 325-amino acid, proton channel carrier protein not coupled to oxidative phosphorylation. It is located in the inner membrane of mitochondria and is linked to the generation of heat. Like other UCPs, BMCP1 facilitates the transfer of anions from the inner to the outer mitochondrial membrane as well as the return transfer of protons from the outer to the inner mitochondrial membrane. In addition, BMCP1 reduces the mitochondrial membrane potential in mammalian cells. BMCP1 is mainly expressed in the brain, while weaker expression is seen in the pituitary and testis. It contains 6 transmembrane domains, 3 motifs typical of mitochondrial energy transfer proteins, and 20 amino acids at the N terminus that are absent in UCP1, UCP2, and UCP3. The BMCP1 protein shares 34, 38, and 39% homology with UCP1, UCP2, and UCP3, respectively. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of BMCP1 (UCP5) of mouse rat and human origin by WB IP IF IHC(P) and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of BMCP1 (UCP5) of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 9016 |
|---|
| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
