Application
Western blot analysis of NRBF2 expression in PC-3 nuclear extract.| Product Name | NRBF2 Antibody (H-93) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-93 mapping at the N-terminus of NRBF2 of human origin |
| Modification Notes | Nuclear hormone receptors function as transcriptional activators when their cognate ligands are bound. Binding of the appropriate ligand induces a conformational change in the nuclear receptor, allowing it to interact with transcriptional coactivators. NRBF2 (Nuclear receptor-binding factor 2), also known as COPR (Comodulator of PPAR and RXR), is thought to act as a transcriptional coactivator by altering the activity of target nuclear receptors. Highly expressed in the liver, placenta and keratinocytes, NRBF2 can interact with at least 7 nuclear receptors including PPARå, PPAR∂ and PPAR©. In the presence of a bound ligand, NRBF2 can interact with nuclear receptors RARå, RAR© and RXRå. NRBF2, which exists as two isoforms due to alternative splicing, is localized to both the nucleus and the cytoplasm. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NRBF2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-93 mapping at the N-terminus of NRBF2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-93 mapping at the N-terminus of NRBF2 of human origin |
| Entrez Gene | 29982 |
|---|
Application
Western blot analysis of NRBF2 expression in PC-3 nuclear extract.| Application Notes | recommended for detection of NRBF2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
