Application
Western blot analysis of Clik1 expression in mouse kidney tissue extract.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing cytoplasmic localization.| Product Name | Clik1 Antibody (L-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of Clik1 of mouse and human origin by WB, IP, IF, IHC(P), ELISA |
| Modification Notes | Clik1 (CLP36 interacting kinase), also known as STK35 (serine/threonine-protein kinase 35) or PDIK1 (PDLIM1-interacting kinase 1), is a 401 amino acid protein that belongs to the protein kinase superfamily. Localized predominately to the nucleus, Clik1 is expressed in the liver, kidney, pancreas, spleen, thymus, prostate and testis. However, coexpression with CLP36 causes relocalization of nuclear Clik1 to the cytoplasm and into actin stress fibers. Actin stress fibers form a dynamic organelle that is important in processes involving cell shape; such as cell migration, cell polarity and cytokinesis. It is suggested that Clik1 may be a novel regulator of the actomyosin cytoskeleton in nonmuscle cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of Clik1 of mouse and human origin by WB IP IF IHC(P) ELISA |
|---|---|
| Tissue Specificity | recommended for detection of Clik1 of mouse and human origin by WB, IP, IF, IHC(P), ELISA |
| Entrez Gene | 140901 |
|---|
Application
Western blot analysis of Clik1 expression in mouse kidney tissue extract.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing cytoplasmic localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
