| Modification Notes |
RSRC1 (arginine/serine-rich coiled-coil 1), also known as BM-011, is a 334 amino acid protein that exists as multiple alternatively spliced isofoms and is encoded by a gene which maps to human chromosome 3. Chromosome 3 houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |