recommended for detection of DNALI1 of mouse, rat and human origin by WB, IP and ELISA
Modification Notes
Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; complexes that transport cellular cargo toward the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNALI1 (dynein, axonemal, light intermediate chain 1), also known as P28, is a 258 amino acid protein involved in flagellar motility. A member of the inner dynein arm light chain family, DNALI1 is widely expressed with highest expression found in testis, and is considered a potential candidate for immotile cilia syndrome (ICS).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of DNALI1 of mouse rat and human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of DNALI1 of mouse, rat and human origin by WB, IP and ELISA