Application
Western blot analysis of HSPBAP1 expression in HeLa whole cell lysate.Application
Western blot analysis of HSPBAP1 expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Product Name | HSPBAP1 Antibody (B-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of HSPBAP1 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488 amino acid cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1. Widely expressed with highest expression in ovary, thymus and pancreas, HSPBAP1 is thought to play a role in mediating cellular stress responses within the cell. Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events. Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis. Three isoforms of HSPBAP1 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of HSPBAP1 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of HSPBAP1 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 79663 |
|---|
Application
Western blot analysis of HSPBAP1 expression in HeLa whole cell lysate.
Application
Western blot analysis of HSPBAP1 expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
