Application
Western blot analysis of LRRC57 expression in non-transfected: (A) and human LRRC57 transfected: (B) 293T whole cell lysates.| Product Name | LRRC57 Antibody (Q-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of LRRC57 of human origin |
| Modification Notes | The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC57 (leucine rich repeat containing 57) is a 239 amino acid protein that contains eight LRR repeats and is encoded by a gene that maps to human chromosome 15q15.2. Chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LRRC57 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other LRRC family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of LRRC57 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of LRRC57 of human origin |
| Entrez Gene | 255252 |
|---|
Application
Western blot analysis of LRRC57 expression in non-transfected: (A) and human LRRC57 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of LRRC57 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other LRRC family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
