epitope mapping at the N-terminus of LRRC57 of human origin
Modification Notes
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRC57 (leucine rich repeat containing 57) is a 239 amino acid protein that contains eight LRR repeats and is encoded by a gene that maps to human chromosome 15q15.2. Chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIFELISA
recommended for detection of LRRC57 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other LRRC family members also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping at the N-terminus of LRRC57 of human origin
Tissue Specificity
epitope mapping at the N-terminus of LRRC57 of human origin
recommended for detection of LRRC57 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other LRRC family members also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.