| Product Name | cadherin-22 Antibody (S-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within a C-terminal cytoplasmic domain of cadherin-22 of human origin |
| Modification Notes | The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-22, also known as CDH22 or PB-cadherin (pituitary and brain cadherin), is an 828 amino acid single-pass type I membrane protein that, characteristic of cadherin proteins, contains five cadherin domains. Expressed predominately in brain, cadherin-22 functions as a Ca2+-dependent cell adhesion protein that is thought to play an important role in tissue formation and morphogenesis, specifically in neural cells during the development and maintenance of brain tissue. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of cadherin-22 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other cadherin family members also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a C-terminal cytoplasmic domain of cadherin-22 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a C-terminal cytoplasmic domain of cadherin-22 of human origin |
| Entrez Gene | 64405 |
|---|
| Application Notes | recommended for detection of cadherin-22 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other cadherin family members also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
