epitope mapping within an internal region of Morc3 of human origin
Modification Notes
The Microrchidia (Morc) family of proteins includes four predicted members in human (Morc1, Morc2, Morc3 and Morc4) and five in mice (Morc1, Morc2a, Morc2b, Morc3 and Morc4). MORC family CW-type zinc finger protein 3 (Morc3), also known as zinc finger CW-type coiled-coil domain protein 3 (ZCWCC3), is a 939 amino acid protein belonging to the MORC family. Ubiquitously expressed in human cell lines, Morc3 contains one CW-type zinc finger and is localized to the nuclear matrix. Morc3 has been shown to play a role in recruiting p53 and SP-100 to promyelocytic leukemia (PML)-nuclear bodies (NBs). Furthermore, Morc3 regulates p53 activation in a manner dependent on Morc3-ATPase activity.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Morc3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of Morc3 of human origin
Tissue Specificity
epitope mapping within an internal region of Morc3 of human origin
Western blot analysis of Morc3 expression in mouse heart (A) and rat skeletal muscle (B) tissue extracts.
Application Notes
recommended for detection of Morc3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.