Application
Western blot analysis of MRP-L39 expression in HEK293 (A), Hep G2 (B), SK-BR-3 (C), NTERA-2 cl.D1 (D), U-937 (E) and MOLT-4 (F) whole cell lysates.Application
Western blot analysis of MRP-L39 expression in non-transfected: (A) and mouse MRP-L39 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of MRP-L39 expression in non-transfected 293T: (A), mouse MRP-L39 transfected 293T: (B) and Hep G2 (C) whole cell lysates.| Product Name | MRP-L39 Antibody (D-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of MRP-L39 of human origin |
| Modification Notes | Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L39 (mitochondrial ribosomal protein L39), also known as MRP-L5, L39mt or L5mt, is a 338 amino acid mitochondrial protein that exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRP-L39 exists as two isoforms produced by alternative splicing. Isoform one of MRP-L39 is ubiquitously expressed while isoform two is specifically expressed in heart. The gene encoding MRP-L39 maps to chromosome 21, which makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MRP-L39 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other MRP family members also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of MRP-L39 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of MRP-L39 of human origin |
| Entrez Gene | 54148 |
|---|
Application
Western blot analysis of MRP-L39 expression in HEK293 (A), Hep G2 (B), SK-BR-3 (C), NTERA-2 cl.D1 (D), U-937 (E) and MOLT-4 (F) whole cell lysates.
Application
Western blot analysis of MRP-L39 expression in non-transfected: (A) and mouse MRP-L39 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of MRP-L39 expression in non-transfected 293T: (A), mouse MRP-L39 transfected 293T: (B) and Hep G2 (C) whole cell lysates.| Application Notes | recommended for detection of MRP-L39 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other MRP family members also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
