Application
Western blot analysis of ZNF294 expression in K-562 (A) and SJRH30 (B) whole cell lysates.| Product Name | ZNF294 Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of ZNF294 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF294 (zinc finger protein 294), also known as RNF160 (RING finger protein 160), is a 1766 amino acid protein that contains one RING-type zinc finger. The RING-type zinc finger, also designated C3HC4 zinc finger, is a conserved cysteine-rich domain that binds two atoms of zinc. Many proteins that contain the RING-type zinc finger have been found to play key roles in the ubiquitination pathway, suggesting that RING-type zinc finger containing proteins may be E3 ubiquitin protein ligases responsible for substrate recognition. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNF294 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of ZNF294 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of ZNF294 of human origin |
| Entrez Gene | 26046 |
|---|
Application
Western blot analysis of ZNF294 expression in K-562 (A) and SJRH30 (B) whole cell lysates.| Application Notes | recommended for detection of ZNF294 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
