Application
Western blot analysis of VIK-1 expression in non-transfected: (A) and human VIK-1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of VIK-1 expression in HeLa whole cell lysate.Application
Western blot analysis of VIK-1 expression in Hep G2 whole cell lysate.| Product Name | VIK-1 Antibody (G-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against VIK-1 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Vav-interacting Krüppel-like protein (VIK-1), also known as zinc finger protein 655 (ZNF655), is a 491 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized primarily to the nucleus, VIK-1 shuttles between the nucleus and the cytoplasm and interacts with c-SH3, one of the three Src domains of Vav that determines its subcellular localization. VIK-1 also plays a roll in cell-cycle progression. VIK-1 interacts with cyclin-dependent kinase 4 (Cdk4) and is involved in inhibiting the G1/S transition of the cell-cycle. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of VIK-1 of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against VIK-1 of human origin |
|---|---|
| Tissue Specificity | raised against VIK-1 of human origin |
| Entrez Gene | 79027 |
|---|
Application
Western blot analysis of VIK-1 expression in non-transfected: (A) and human VIK-1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of VIK-1 expression in HeLa whole cell lysate.
Application
Western blot analysis of VIK-1 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of VIK-1 of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
