Application
Western blot analysis of MOB1B expression in Ramos whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining.| Product Name | MOB1B Antibody (C-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of MOB1B of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. The mammalian homologs MST1 and MST2, also designated Krs-2 and Krs-1, respectively, are major regulators of cell proliferation and survival during development. MST1/MST2 phosphorylize MOBKL1A and MOBKL1B in an MST1/MST2-dependent manner in mitosis and in response to okadaic acid or H2O2. MOBKL1A and MOBKL1B, also designated MOB1A and MOB1B, bind to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase. Therefore, MOBKL1A and MOBKL1B participate in cell cycle checkpoint control and tumor inhibition. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of MOB1B of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of MOB1B of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 92597 |
|---|
Application
Western blot analysis of MOB1B expression in Ramos whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
