Application
Western blot analysis of PIG-V expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing nuclear and cytoplasmic staining.| Product Name | PIG-V Antibody (A-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against porcine-V of human origin |
| Modification Notes | Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit various functions but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor, which acts as a membrane anchor for many eukaryotic cells. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex (GPI-N-acetylglucosaminyltransferase or GPI-GnT) and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis. PIG-V, a 493 amino acid protein, functions as a mannosyltransferaise in GPI anchor biosynthesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of porcine-V of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against porcine-V of human origin |
|---|---|
| Tissue Specificity | raised against porcine-V of human origin |
| Entrez Gene | 55650 |
|---|
Application
Western blot analysis of PIG-V expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing nuclear and cytoplasmic staining.| Application Notes | recommended for detection of porcine-V of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
