Application
Western blot analysis of Neuroplastin expression in Hep G2 whole cell lysate.| Product Name | Neuroplastin Antibody (R-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against Neuroplastin of human origin |
| Modification Notes | Neuroplastin, also known as NPTN, GP55, GP65, SDR1 (stromal cell-derived receptor), np55 or SDFR1, is a single pass type I membrane protein that is predominantly expressed in brain and localizes to the cell membrane. Existing as a member of the Immunoglobulin (Ig) superfamily, Neuroplastin contains at least one Ig-like C2-type domain and at least one Ig-like V-type domain. Neuroplastin functions as a cell adhesion molecule and participates in cell-substrate or cell-cell interactions. Neuroplastin is believed to play a key role in mediating long-term changes in synaptic activity. In addition, Neuroplastin is overexpressed in breast cancers, suggesting a possible role in tumorigenesis. Due to alternative splicing events, Neuroplastin exists in at least two isoforms, namely np55 and np65. The np55 isoform is ubiquitously expressed, whereas the np65 isoform is exclusively expressed in brain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of Neuroplastin of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against Neuroplastin of human origin |
|---|---|
| Tissue Specificity | raised against Neuroplastin of human origin |
| Entrez Gene | 27020 |
|---|
Application
Western blot analysis of Neuroplastin expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of Neuroplastin of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
