| Product Name | RNH1 Antibody (M-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 157-456 mapping at the C-terminus of RNH1 of mouse origin |
| Modification Notes | RNH1, the placental ribonuclease (RNase) inhibitor, is an acidic 460-amino acid protein which contains an unusually high content of leucine and cysteine residues. It is a member of a family of proteinaceous cytoplasmic RNase inhibitors that are expressed in many tissues and bind to both intracellular and extracellular RNases in the cytosol. RNH1 binds to a diverse variety of mammalian RNases and holds them in a latent form. It is also important in the control of mRNA turnover. RNH1inhibits angiogenesis by reversibly binding angiogenin, a member of the RNaseA superfamily. Because angiogenesis is necessary for the growth and metastasis of tumors, RNH1 may play an important role in cancer gene therapy. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RNH1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 157-456 mapping at the C-terminus of RNH1 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 157-456 mapping at the C-terminus of RNH1 of mouse origin |
| Entrez Gene | 6050 |
|---|
| Application Notes | recommended for detection of RNH1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
