| Product Name | PRKX Antibody (M-67) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 61-127 mapping near the N-terminus of PRKX of mouse origin |
| Modification Notes | The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. PRKX (protein kinase, X-linked), also known as PKX1, is a 358 amino acid member of the AGC Ser/Thr protein kinase family and belongs to the subfamily of cAMP-dependent kinases. Highly expressed in adult and fetal brain, lung and kidney with lower expression in adult heart, pancreas, liver, placenta, skeletal muscle and fetal liver, PRKX is developmentally regulated and contains one protein kinase domain and one C-terminal AGC-kinase domain. PRKX is essential for macrophage differentiation and participates in renal epithelial cell migration. Disruption of the gene encoding PRKX due to a chromosomal aberration can result in sex reversal disorder. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PRKX of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 61-127 mapping near the N-terminus of PRKX of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 61-127 mapping near the N-terminus of PRKX of mouse origin |
| Entrez Gene | 19108 |
|---|
| Application Notes | recommended for detection of PRKX of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
