epitope mapping within an internal region of DHRS13 of human origin
Modification Notes
DHRS13 (dehydrogenase/reductase SDR family member 13), also known as UNQ419/PRO853, is a 377 amino acid secreted protein belonging to the short-chain dehydrogenases/reductases (SDR) family. DHRS13 is presumed to function as an oxidoreductase and is phosphorylated, potentially by ATM or ATR, upon DNA damage. DHRS13 exists as two isoforms produced by alternative splicing events. The gene encoding DHRS13 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are associated with chromosome 17.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of DHRS13 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other DHRS family members also reactive with additional species, including canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of DHRS13 of human origin
Tissue Specificity
epitope mapping within an internal region of DHRS13 of human origin
Western blot analysis of DHRS13 expression in non-transfected: (A) and human DHRS13 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of DHRS13 expression in Daudi (A) and MOLT-4 (B) whole cell lysates.
Application Notes
recommended for detection of DHRS13 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other DHRS family members also reactive with additional species, including canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.