Application
Western blot analysis of Myozenin 2 expression in mouse heart tissue extract.| Product Name | Myozenin 2 Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 51-100 mapping near the N-terminus of Myozenin 2 of human origin |
| Modification Notes | The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to å-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Myozenin 2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 51-100 mapping near the N-terminus of Myozenin 2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 51-100 mapping near the N-terminus of Myozenin 2 of human origin |
| Entrez Gene | 51778 |
|---|
Application
Western blot analysis of Myozenin 2 expression in mouse heart tissue extract.| Application Notes | recommended for detection of Myozenin 2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
