Application
Western blot analysis of KIF14 expression in MCF7 whole cell lysate.| Product Name | KIF14 Antibody (H-240) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1141-1380 mapping within an internal region of KIF14 of human origin |
| Modification Notes | Kinesin is a cytoskeletal motor protein involved in axonal transport and cell division. The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination and speed of transportation of a variety of important functional molecules, including mRNA. KIFs are involved in neuronal function and development. Kinesin family member 14 (KIF14) is an overexpressed potential oncogene in the 1q region of genomic gain in breast cancer cell lines associated with poor prognosis breast cancer. The gain of chromosome 1q likely reflects oncogene amplification. KIF14 is a potential therapeutic target and indicator of oncogenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KIF14 of m and h origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1141-1380 mapping within an internal region of KIF14 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1141-1380 mapping within an internal region of KIF14 of human origin |
Application
Western blot analysis of KIF14 expression in MCF7 whole cell lysate.| Application Notes | recommended for detection of KIF14 of m and h origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
