Application
Western blot analysis of CLLU1 expression in CCRF-CEM (A), K-562 (B), MEG-01 (C), Ramos (D), human PBL (E) and AML-193 (F) whole cell lysates.| Product Name | CLLU1 Antibody (N-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of CLLU1 of human origin |
| Modification Notes | Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by the presence of small mature lymphocytes, intense accumulation of monoclonal B cells and a characteristic CD5 and CD19 co-expression phenotype. While the clinical course of CLL can be highly variable, a CLL specific protein known as CLLU1 (chronic lymphocytic leukemia up-regulated 1) is expressed in CLL patients, with high CLLU1 expression associated with shorter overall survival. Consisting of 121 amino acids, CLLU1 has been predicted to interact with interleukin 4 receptor (IL-4R) and is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CLLU1 of human origin by WB, IP, IF and ELISA non cross-reactive with CLLU1OS: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of CLLU1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of CLLU1 of human origin |
| Entrez Gene | 574028 |
|---|
Application
Western blot analysis of CLLU1 expression in CCRF-CEM (A), K-562 (B), MEG-01 (C), Ramos (D), human PBL (E) and AML-193 (F) whole cell lysates.| Application Notes | recommended for detection of CLLU1 of human origin by WB, IP, IF and ELISA non cross-reactive with CLLU1OS: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
