| Product Name | RNF181 Antibody (H-83) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-83 mapping at the N-terminus of RNF181 of human origin |
| Modification Notes | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF181 (RING finger protein 181) is a 153 amino acid protein that contains one RING-type zinc finger and belongs to the RNF181 family. RNF181 is auto-ubiquitinated as part of the enzymatic reaction, and upon DNA damage, RNF181 is phosphorylated by ATM or ATR. RNF181 demonstrates highest levels of expression in liver and heart, moderate levels in placenta, lung, liver, kidney, pancreas, and lower levels in brain and skeletal muscle. The RNF181 gene is conserved in chimpanzee, dog, cow, mouse, rat, zebrafish and fruit fly, and maps to human chromosome 2p11.2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RNF181 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-83 mapping at the N-terminus of RNF181 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-83 mapping at the N-terminus of RNF181 of human origin |
| Entrez Gene | 51255 |
|---|
| Application Notes | recommended for detection of RNF181 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
