Application
Western blot analysis of CCDC108 expression in WI 38 whole cell lysate.| Product Name | CCDC108 Antibody (E-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of CCDC108 of human origin |
| Modification Notes | CCDC108 (coiled-coil domain containing 108) is a 1,925 amino acid single-pass membrane protein that contains one MSP domain and is encoded by a gene that maps to human chromosome 2q35. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CCDC108 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other CCDC family members also reactive with additional species, including equine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of CCDC108 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of CCDC108 of human origin |
| Entrez Gene | 255101 |
|---|
Application
Western blot analysis of CCDC108 expression in WI 38 whole cell lysate.| Application Notes | recommended for detection of CCDC108 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other CCDC family members also reactive with additional species, including equine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
