epitope corresponding to amino acids 1-130 mapping at the N-terminus of MLF2 of human origin
Modification Notes
Myeloid leukemia factor (MLF) proteins typically demonstrate highest levels of expression in testis, ovary, skeletal muscle, heart, kidney and colon tissues, and lower levels of expression in spleen, thymus, and peripheral blood leukocytes. MLF proteins play a role in normal hemopoietic differentiation as well as in erythroid/myeloid lineage switching. MLF2 is a ubiquitously expressed, 248-amino acid protein which shares 40% sequence identity with myeloid leukemia factor 1 (MLF1). MLF2 maps to chromosome 12p13, a region that is often associated with translocations in acute leukemias of lymphoid and myeloid origin. However, no alterations in the structure of the MLF2 locus in patients shown to have 12p translocations have been discovered.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of MLF2 (myeloid leukemia factor 2) of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-130 mapping at the N-terminus of MLF2 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-130 mapping at the N-terminus of MLF2 of human origin
Western blot analysis of MLF2 expression in non-transfected: (A) and human MLF2 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of MLF2 (myeloid leukemia factor 2) of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.