epitope corresponding to phosphorylated Ser 455 of ATP-citrate synthase of human origin
Modification
Phosphoralated
Modification Notes
ATP-citrate synthase, also designated ATP-citrate lyase or citrate cleavage enzyme, is a cytoplasmic homotetramer belonging to the succinate/malate CoA ligase family. The gene coding for this protein maps against chromosome 17q12-q21. ATP-citrate synthase catalyses the formation of acetyl-CoA and oxaloacetate from citrate and CoA. This product, Acetyl-CoA, is necessary for both fatty acid and cholesterol biosynthesis. ATP citrate-lyase is important in the biosynthesis of acetylcholine in nervous tissue.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIFIPWB
recommended for detection of phosphorylated Ser 455 of ATP-citrate synthase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: WB:1:100~1:200 IF:1:20~1:100 ELISA:1:1000~5000 IP:1:20~1:100
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to phosphorylated Ser 455 of ATP-citrate synthase of human origin
Tissue Specificity
epitope corresponding to phosphorylated Ser 455 of ATP-citrate synthase of human origin
Antibodies tested is p-ATP-citrate synthase (Ser 455): (A,B,C) and ATP-citrate synthase (C-20): (D,E,F).
Application Notes
recommended for detection of phosphorylated Ser 455 of ATP-citrate synthase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: WB:1:100~1:200 IF:1:20~1:100 ELISA:1:1000~5000 IP:1:20~1:100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.