Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis showing cytoplasmic staining of cells in seminiferus ducts & Leydig cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis showing cytoplasmic staining of cells in seminiferus ducts & Leydig cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of TRAX expression in non-transfected 293T: (A), mouse TRAX transfected 293T: (B) and NIH/3T3 (C) whole cell lysates.| Product Name | TRAX Antibody (FL-290) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-290 representing full length TRAX of human origin |
| Modification Notes | TRAX (translin-associated factor X), also known as TSNAX, is a nuclear protein that interacts with translin, a DNA-binding protein involved in breakpoint junctions of chromosomal translocations. Expressed highly in the brain and testis, TRAX contains an N-terminal bipartite nuclear localization signal (NLS) and a leucine zipper domain. The NLS may be involved in the nuclear transport of translin, while the leucine zipper domain is essential for interactions between TRAX and other proteins. When TRAX is complexed with translin, the two proteins can interact with the protein kinase activator C1D, allowing the complex to participate in DNA double-stranded break repair and dentritic RNA processing. TRAX also functions as a transcriptional regulator of GAP-43, a growth-associated protein found in growth cones, suggesting a possible role in axonal regeneration and cell proliferation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of TRAX of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-290 representing full length TRAX of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-290 representing full length TRAX of human origin |
| Entrez Gene | 7257 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis showing cytoplasmic staining of cells in seminiferus ducts & Leydig cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis showing cytoplasmic staining of cells in seminiferus ducts & Leydig cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of TRAX expression in non-transfected 293T: (A), mouse TRAX transfected 293T: (B) and NIH/3T3 (C) whole cell lysates.| Application Notes | recommended for detection of TRAX of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
