Application
Western blot analysis of glypican-6 expression in K-562 whole cell lysate.| Product Name | glypican-6 Antibody (X-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of glypican-6 of human origin by WB, IP and ELISA |
| Modification Notes | The glypicans are a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that are involved in the control of cell growth and division. Glypican-6, also known as GPC6, is a 555 amino acid protein that exists as both a lipid-anchored cell membrane peptide, as well as a secreted protein that is released into the extracellular space. Expressed ubiquitously with highest expression in liver, kidney, colon, ovary and small intestine, glypican-6 functions as a cell surface receptor that is thought to bind to a variety of proteins, including growth factors, proteases and extracellular matrix proteins. The gene encoding glypican-6 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of glypican-6 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of glypican-6 of human origin by WB, IP and ELISA |
| Entrez Gene | 10082 |
|---|
Application
Western blot analysis of glypican-6 expression in K-562 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
