Application
Western blot analysis of USP12 expression in non-transfected: (A) and mouse USP12 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of USP12 expression in non-transfected: (A) and mouse USP12 transfected: (B) 293T whole cell lysates.| Product Name | USP12 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of USP12 of human origin |
| Modification Notes | The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP12 (ubiquitin specific peptidase 12), also known as UBH1 or USP12L1, is a 370 amino acid protein belonging to the peptidase C19 family and the USP12/USP46 subfamily. Considered a deubiquitinating enzyme, it is suggested that USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have high activity. The gene encoding USP12 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of USP12 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other USP family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of USP12 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of USP12 of human origin |
| Entrez Gene | 219333 |
|---|
Application
Western blot analysis of USP12 expression in non-transfected: (A) and mouse USP12 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of USP12 expression in non-transfected: (A) and mouse USP12 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of USP12 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other USP family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
