Application
Western blot analysis of ZNHIT6 expression in HeLa whole cell lysate.Application
Western blot analysis of ZNHIT6 expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human intestine tissue showing membrane staining.| Product Name | ZNHIT6 Antibody (Y-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ZNHIT6 of human origin |
| Modification Notes | ZNHIT6 (zinc finger, HIT type 6), also known as BCD1 (box C/D snoRNA essential 1 homolog), is a 470 amino acid protein that contains one HIT-type zinc finger. The gene encoding ZNHIT6 localizes to chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf181 gene product has been provisionally designated C1orf181 pending further characterization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of ZNHIT6 of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNHIT6 of human origin |
|---|---|
| Tissue Specificity | raised against ZNHIT6 of human origin |
| Entrez Gene | 54680 |
|---|
Application
Western blot analysis of ZNHIT6 expression in HeLa whole cell lysate.
Application
Western blot analysis of ZNHIT6 expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human intestine tissue showing membrane staining.| Application Notes | recommended for detection of ZNHIT6 of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
