Application
Western blot analysis of LRRC3B expression in HeLa whole cell lysate.Application
Western blot analysis of LRRC3B expression in non-transfected: (A) and human LRRC3B transfected: (B) 293 whole cell lysates.Application
Western blot analysis of LRRC3B expression in SW480 whole cell lysate.| Product Name | LRRC3B Antibody (S-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of LRRC3B of human origin |
| Modification Notes | Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LRRC3B of mouse and human origin by WB, IP, IF and ELISA non cross-reactive with other LRRC family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of LRRC3B of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of LRRC3B of human origin |
| Entrez Gene | 116135 |
|---|
Application
Western blot analysis of LRRC3B expression in HeLa whole cell lysate.
Application
Western blot analysis of LRRC3B expression in non-transfected: (A) and human LRRC3B transfected: (B) 293 whole cell lysates.
Application
Western blot analysis of LRRC3B expression in SW480 whole cell lysate.| Application Notes | recommended for detection of LRRC3B of mouse and human origin by WB, IP, IF and ELISA non cross-reactive with other LRRC family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
