Application
Western blot analysis of ZNF141 expression in Jurkat whole cell lysate.| Product Name | ZNF141 Antibody (V-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of ZNF141 of human origin by WB, IP and ELISA |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF141 (Zinc finger protein 141) is a 474 amino acid nuclear protein that contains one KRAB domain and eleven C2H2-type zinc fingers. ZNF141 acts as a transcription repressor and is expressed ubiquitously at low levels. The gene encoding ZNF141 maps within a region of human chromosome 4 that is deleted in Wolf-Hirschhorn syndrome, a condition that leads to severe abnormalities such as microencephaly, mental retardation, cleft lip and/or cleft palate, seizures and poor muscle tone. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ZNF141 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of ZNF141 of human origin by WB, IP and ELISA |
| Entrez Gene | 7700 |
|---|
Application
Western blot analysis of ZNF141 expression in Jurkat whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
