recommended for detection of TRABD of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine
Modification Notes
TRABD (TraB domain-containing protein) is a 376 amino acid protein whose gene is encoded by human chromosome 22, which contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. There are two isoforms of TRABD that are produced as a result of alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of TRABD of mouse rat and human origin by WB IP and ELISA also reactive with additional species including canine
Tissue Specificity
recommended for detection of TRABD of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine