recommended for detection of MFSD3 of mouse, rat and human origin by WB, IP and ELISA
Modification Notes
The Major facilitator superfamily consists of presumed carbohydrate transporters with 10-12 membrane-spanning domains. MFSD3 (Major facilitator superfamily domain-containing protein 3) is a 412 amino acid multi-pass membrane protein that is likely a carrier that transports small solutes by using chemiosmotic ion gradients. Significantly, a related protein, MFSD2, may play a role in placenta morphogenesis and may also be involved in adaptive thermogenesis. The gene encoding MFSD3 maps to chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of MFSD3 of mouse rat and human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of MFSD3 of mouse, rat and human origin by WB, IP and ELISA