recommended for detection of ZNF605 of human origin by WB, IP and ELISA
Modification Notes
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF605 (zinc finger protein 605) is a 641 amino acid nuclear protein that belongs to the Krüppel C2H2-type zinc-finger protein family and may play a role in transcriptional regulation. Containing one KRAB domain and seventeen C2H2-type zinc fingers, ZNF605 is encoded by a gene that maps to human chromosome 12q24.33. Chromosome 12 encodes over 1,100 genes, comprises approximately 4.5% of the human genome and is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ZNF605 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of ZNF605 of human origin by WB, IP and ELISA
Application
Application
Western blot analysis of ZNF605 expression in Hep G2 whole cell lysate.
Application Notes
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.