recommended for detection of VAMP-5 of human origin by WB, IP and ELISA
Modification Notes
The Syntaxin family of proteins anchor themselves to the cytoplasmic surface of cellular membranes and bind to proteins that are involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25 kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs are vesicular factors that are important components of the machinery controlling docking and/or fusion of secretory vesicles. VAMPs are thought to function as inhibitors of exocytosis. VAMP-5 (vesicle-associated membrane protein 5) is a 116 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. VAMP-5 may participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or Glut4 trafficking. Containing one v-SNARE coiled-coil homology domain, VAMP-5 localizes to the Golgi apparatus and is encoded by a gene located on human chromosome 2p11.2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of VAMP-5 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of VAMP-5 of human origin by WB, IP and ELISA