| Product Name | ZNF512B Antibody (K-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ZNF512B of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF512B (zinc finger protein 512B), also known as GM632, is an 892 amino acid protein that localizes to the nucleus and belongs to the krueppel C2H2-type zinc-finger protein family. Thought to be involved in transcriptional regulation, ZNF512B contains seven C2H2-type zinc fingers and is encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ZNF512B of mouse and human origin by WB, IF and ELISA non cross-reactive with other ZNF family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZNF512B of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZNF512B of human origin |
| Entrez Gene | 57473 |
|---|
| Application Notes | recommended for detection of ZNF512B of mouse and human origin by WB, IF and ELISA non cross-reactive with other ZNF family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
