| Product Name | glypican-6 Antibody (T-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The glypicans are a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that are involved in the control of cell growth and division. Glypican-6, also known as GPC6, is a 555 amino acid protein that exists as both a lipid-anchored cell membrane peptide, as well as a secreted protein that is released into the extracellular space. Expressed ubiquitously with highest expression in liver, kidney, colon, ovary and small intestine, glypican-6 functions as a cell surface receptor that is thought to bind to a variety of proteins, including growth factors, proteases and extracellular matrix proteins. The gene encoding glypican-6 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of glypican-6 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other gypican family members also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of glypican-6 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of glypican-6 of human origin |
| Entrez Gene | 10082 |
|---|
| Application Notes | recommended for detection of glypican-6 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other gypican family members also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
