epitope corresponding to amino acids 241-310 mapping within an internal region of Matrilin-3 of human origin
Modification Notes
The matrilin family of secreted extracellular matrix proteins is comprised of Matrilin-1 through Matrilin-4. Matrilin-1 is a homotrimer that binds to collagen and is a component of the extracellular matrix of nonarticular cartilage. It is secreted primarily by chondrocytes in a characteristic spatial, temporal and developmental stage-specific pattern during skeletogenesis. Matrilin-2 is a secreted protein involved in matrix assembly. Matrilin-3 is a secreted protein expressed solely in cartilaginous tissues. It is important in the extracellular matrix of cartilage and in the formation of extracellular filamentous networks. Matrilin-4, expressed in embryonic kidney, lung and placenta, is a secreted protein important to the extracellular matrix of cartilage.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Matrilin-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 241-310 mapping within an internal region of Matrilin-3 of human origin
Tissue Specificity
epitope corresponding to amino acids 241-310 mapping within an internal region of Matrilin-3 of human origin
Western blot analysis of Matrilin-3 expression in non-transfected: (A) and mouse Matrilin-3 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Matrilin-3 expression in HeLa whole cell lysate.
Application Notes
recommended for detection of Matrilin-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.