Western blot analysis of SETD4 expression in HEK293 (A), K-562 (B) and HL-60 (C) whole cell lysates and rat cerebellum (D) and mouse testis (E) tissue extracts.
SETD4 (SET domain-containing protein 4) is a 440 amino acid protein that contains one SET domain and is expressed as three isoforms produced by alternative splicing. The gene that encodes SETD4 maps to human chromosome 21. The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SETD4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoforms A, B or 3 also reactive with additional species, including equine, canine, bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of SETD4 of human origin
Tissue Specificity
epitope mapping within an internal region of SETD4 of human origin
Western blot analysis of SETD4 expression in HEK293 (A), K-562 (B) and HL-60 (C) whole cell lysates and rat cerebellum (D) and mouse testis (E) tissue extracts.
Application Notes
recommended for detection of SETD4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoforms A, B or 3 also reactive with additional species, including equine, canine, bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.