LZTFL1 (Leucine zipper transcription factor-like protein 1) is a 299 amino acid protein that shares 90% sequence identity with its mouse counterpart. While LZTFL1 is expressed in liver, brain, lung and kidney during early development, it is found in testis, heart, thymus, pancreas, ovary, prostate, colon, skeletal muscle and small intestine in adult tissues. LZTFL1 has a leucine zipper pattern and several coiled-coil domains, suggesting a possible role in transcriptional regulation. The gene encoding LZTFL1 is located in a tumor suppressor region on chromosome 3, indicating that LZTFL1 may be a potential tumor suppressor. Two isoforms of LZTFL1 exist due to alternative polyadenylation events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of LZTFL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-299 representing full length LZTFL1 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-299 representing full length LZTFL1 of human origin
Western blot analysis of LZTFL1 expression in Jurkat (A) and HS 181.Tes (B) whole cell lysates.
Application Notes
recommended for detection of LZTFL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.