recommended for detection of ARL2 of human origin by WB, IP and ELISA
Modification Notes
ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of Cholera Toxin. ARF’s are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL2 (ADP-ribosylation factor-like protein 2), also known as ARFL2, is a 184 amino acid protein that belongs to the ARF family of ADP-ribosylation factors. Expressed ubiquitously, ARL2 functions as a component of a secretory pathway that is involved in the calcium-dependent release of acetylcholine. Additionally, ARL2 plays a role in the folding of tubule proteins, thereby playing an important role in microtubule dynamics and cell cycle progression. Unlike other members of the ARF family, ARL2 does not act as an activator of the catalytic subunit of Cholera Toxin.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ARL2 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of ARL2 of human origin by WB, IP and ELISA