Application
Western blot analysis of SURF-6 expression in Jurkat whole cell lysate.Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing nuclear staining.| Product Name | SURF-6 Antibody (F-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against SURF-6 of human origin |
| Modification Notes | SURF-6 (Surfeit locus protein-6) is a 361 amino acid protein that localizes to granular components of the nucleolus. Expressed ubiquitously with expression levels regulated during the cell cycle, SURF-6 is thought to function as a housekeeping protein that binds both RNA and DNA in vitro and may be involved in ribosome assembly and biosynthesis. In mice, cells lacking SURF-6 are nonviable, further implicating a role for SURF-6 in ribosome biogenesis and, possibly, proper cell cycle progression. Human SURF-6 shares structural similarity with its fish and mouse orthologs, suggesting an evolutionary conserved role between species. SURF-6 is encoded by a gene that is located on chromosome 9 in the Surfeit gene locus, which is one of the tightest gene clusters in the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of SURF-6 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against SURF-6 of human origin |
|---|---|
| Tissue Specificity | raised against SURF-6 of human origin |
| Entrez Gene | 6838 |
|---|
Application
Western blot analysis of SURF-6 expression in Jurkat whole cell lysate.
Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing nuclear staining.| Application Notes | recommended for detection of SURF-6 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
