| Product Name | Calpain 12 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Calpains are calcium-activated thiol proteases. They are heterodimers with one large subunit and one small subunit. The large subunit varies between family members and can be active without the small subunit. Calpains are involved in intracellular processing of proteins. Calpain 12 is a typical calpain with protease and calcium binding domains. It is expressed ubiquitously, with a very high level of expression in the cortex of the hair follicle during the hair cycle anagen phase. The modification of Calpain 12, together with å Enolase and ATP5B, may play a significant role in plaque deposition of the brain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Calpain 12 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 41-100 mapping near the N-terminus of Calpain 12 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 41-100 mapping near the N-terminus of Calpain 12 of human origin |
| Entrez Gene | 147968 |
|---|
| Application Notes | recommended for detection of Calpain 12 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
