Calpains are calcium-activated thiol proteases. They are heterodimers with one large subunit and one small subunit. The large subunit varies between family members and can be active without the small subunit. Calpains are involved in intracellular processing of proteins. Calpain 13, also called Sol H, is the most divergent caplain member. It is a homolog of Sol, an optic lobe gene product of Drosophila. Calpain 13 is a member of the non-EF-hand subfamily of calpains. Calpain 13 is composed of four domains and consists of 423 amino acid residues. It has a limited tissue distribution but has been found in human brain, testis and lung.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Calpain 13 of mouse and rat origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 366-665 mapping at the C-terminus of Calpain 13 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 366-665 mapping at the C-terminus of Calpain 13 of mouse origin