Application
Western blot analysis of Fnk expression in mouse lung tissue extract.| Product Name | Fnk Antibody (H-140) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Plks (polo-like kinases) encode serine/threonine kinases that are closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively (1-4). Polo-like kinases, which include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk (for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell proliferation (5). Plk protein accumulates in the cell during S and G2 phases of the cell cycle, and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis (2). Snk and Fnk are immediate-early response genes that are first expressed during G1 phase (5,6). Fnk expression peaks in late S and G2 phases, and it may play a role in regulating the onset of M phase (7). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Fnk of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 321-460 mapping to an internal region of Fnk of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 321-460 mapping to an internal region of Fnk of human origin |
| Entrez Gene | 1263 |
|---|
Application
Western blot analysis of Fnk expression in mouse lung tissue extract.| Application Notes | recommended for detection of Fnk of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
