| Product Name | TFIIA-γ Antibody (FL-109) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors (1). Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH (1-3). Recognition of the TATA binding element by TBP, one of the first steps in transcription initiation, may be regulated by TFIIA (4,5). TFIIA consists of three subunits designated TFIIA-å, TFIIA-∫ and TFIIA-©, and it interacts with both TBP and a TAF (TBP-associated factor) (6,7). It has been demonstrated that the basic region of TBP is essential for TFIIA-dependent function of TBP (8). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISAGSChIP |
| recommended for detection of TFIIA-&gamma of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-109 representing full length TFIIA-&gamma of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-109 representing full length TFIIA-γ of human origin |
| Entrez Gene | 2958 |
|---|
| Application Notes | recommended for detection of TFIIA-&gamma of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
