| Product Name | PCNA Antibody (at-263) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The proliferating cell nuclear antigen (PCNA), a protein synthesized in early G1 and S phases of the cell cycle, functions in cell cycle progression, DNA replication and DNA repair. In early S phase, PCNA exhibits granular distribution and is absent from the nucleoli; however, in late S phase, it relocates to the nucleoli. PCNA exists in two basic forms: one involved in ongoing DNA replication, which localizes specifically to the nucleus, and a second, soluble form, not implicated in constant synthesis. Interestingly, the latter form degrades in the presence of organic solvents, rendering it undetectable by histological methods in tissues using organic fixatives, and thus also providing a method of visualizing only the synthesizing form. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PCNA of Arabidopsis thaliana, Nicotiana tabacum, Lycopersicon esculentum, Zea mays and Pisum sativum origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-263 representing full length PCNA of Arabidopsis thaliana origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-263 representing full length PCNA of Arabidopsis thaliana origin |
| Application Notes | recommended for detection of PCNA of Arabidopsis thaliana, Nicotiana tabacum, Lycopersicon esculentum, Zea mays and Pisum sativum origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
